PCL - Slide 4

Musto (2025)

At diagnosis, the patient basically meets the criteria for multiple myeloma. However, because of the presence of more than 5% plasma cells in the peripheral blood, the diagnosis of primary plasma cell leukemia, the most aggressive form of plasma cell dyscrasias, was made. There was hypercalcemia of 3.5 mmol/L, with no impaired renal function and no anemia, but extensive osteolytic lesions in the upper body. In addition, an IgG-kappa paraprotein of 40 g/L was detected.

Neutrophils

Lymphocytes

Monocytes

Eosinophils

Basophils

Plasma Cells

XN Scatterplots

wdf

wnr

wpc

Lymphocytes

Monocytes

Neutrophils

Eosinophils

Basophils

Leukocytes

Basophils

NRBCs

Debris

Erythrocytes

Reticulocytes

RBC fragments

Platelets

immature platelets

Lymphocytes

Monocytes

Granulocytes

Reference

Immunophenotype

CD45-

CD19-

CD20-

CD38++

CD138+

CD56+

CD27-

CD81+

CD117-

Peripheral blood

Plasma cells